|Call||Career Development Fellowship (CDF)|
Metabolic and molecular ecological evolution of opportunistic pulmonary fungal co-infections (MeMoF)
|Mbarara University of Science and Technology (MUST)||Uganda|
Mbarara University of science and technology
|Type||Name||Title||University||Start Date||End Date|
|Master of Science||Kiiza Israel Njovu||PULMONARY MYCOSES DIAGNOSED FROM SPUTUM SPECIMENS OF INDIVIDUALS WITH CLINICAL SIGNS OF PULMONARY TUBERCULOSIS AT MBARARA REGIONAL REFERRAL HOSPITAL||Mbarara University of Science and Technology||2019||2021|
|Master of science||Guti Walker||ASSESSMENT OF ANTIMICROBIAL ACTIVITY, BACTERIAL AND FUNGAL CONTAMINANTS OF COMMON HERBAL MEDICINAL REMEDIES IN MBARARA DISTRICT, SOUTH WESTERN UGANDA||Mbarara University of Science and Technology||2020||2021|
|Master of science||Kumureeba Lauben||ELUCIDATING THE IMPACT OF BACTERIAL SYMBIOSIS ON THE VIRULENCE OF FUNGI ISOLATED AT MBARARA REGIONAL REFERRAL HOSPITAL||Mbarara University of Sceince and Technology||2020||2022|
|Master of Science||Pauline Petra Nalumaga||Phenotypic and genetic diversity of antifungal resistant candida species associated with Vulvo-Viginal Candidiasis||Mbarara university of Science and Technology||2021||2022|
|Master of Science||Thomas Ssemakadde||Hetero-resistance to common anti-fungals used against yeast isolates at Mbarara regional referral hospital||Mbarara University of Science and Technology||2021||2022|
|PhD||Benson Musingunzi||MOLECULAR CHARACTERIZATION OF CANDIDA SPECIES CAUSING OROPHARYNGEAL CANDIDIASIS IN HIV INFECTED PATIENTS IN UGANDA||Makerere University||2021||2025|
|Role||Committee/board||Start Date||End Date|
|Organising committee member||Medical Mycology TraineeSeminar Series||2020||2025|
|University of Birmingham, United Kingdom||PhD||2019-10-19|
|University of Aberdeen, United Kingdom||MRes||2015-09-28|
|Mbarara University of Science and Technology, Uganda||MSc||2014-08-08|
Medical Mycolog, fungal immunology, infection biology
Pulmonary mycoses are important diseases of the respiratory tract caused by pulmonary fungal pathogens. These pathogens are responsible for significant morbidity and mortality rates worldwide; however, less attention has been paid to them. In this study we determined the prevalence of pulmonary fungal pathogens among individuals with clinical features of pulmonary tuberculosis at Mbarara Regional Referral Hospital.
This was a hospital based cross sectional survey. Sputum samples were collected from each study participant. For each sample, the following tests were performed: Sabouraud dextrose agar for fungal culture, GeneXpert for Mycobacteria tuberculosis (MTB) and potassium hydroxide for fungal screening. Filamentous fungal growth and yeasts were further examined with lactophenol cotton blue staining and germ tube respectively.
Out of 113 study participants, 80 (70.7%) had pulmonary fungal pathogens whilst those with pulmonary tuberculosis numbered five (4.4%). Candida albicans [21 (22.58%)] and Aspergillus species [16 (17.20%)] were the pathogens most identified among others. Two (1.7%) TB GeneXpert positive participants had fungal pathogens isolated from their sputum samples. We established a prevalence of 57 (71.3%) for pulmonary fungal pathogen (PFP) isolates, three (60.0%) for MTB in HIV positive patients and 18 (22.5%) for PFP, and zero (0.0%) for MTB in HIV negative patients. On the other hand, two (100%) HIV positive patients had both PFP isolates and MTB.
Our findings highlight the diversity of neglected pulmonary fungal pathogens whose known medical importance in causing pulmonary mycoses cannot be overemphasised. Therefore this presents a need for routine diagnosis for pulmonary mycoses among TB suspects and set-up of antimicrobial profile for pulmonary fungal isolates to support clinical management of these cases.