EDCTP Alumni Network

Kengne AP , author
Libend CN , author
Dzudie A , author
Menanga A , author
Dehayem MY , author
Kingue S , author
Sobngwi E , author

2014-10-01

The Pan African medical journal

PMID: 25838859
PMC: PMC4377096
DOI: 10.11604/pamj.2014.19.231.2608

Pheiffer C , author
Erasmus RT , author
Kengne AP , author
Matsha TE , author

2015-12-01

Clinical biochemistry

PMID: 26656639
DOI: 10.1016/j.clinbiochem.2015.11.021

Yako YY , author
Madubedube JH , author
Kengne AP , author
Erasmus RT , author
Pillay TS , author
Matsha TE , author

2015-12-01

African health sciences

PMID: 26958016
PMC: PMC4765404
DOI: 10.4314/ahs.v15i4.14

Kufe NC , author
Masemola M , author
Chikowore T , author
Kengne AP , author
Olsson T , author
Goedecke JH , author
Micklesfield LK , author

2019-01-01

BMJ open

PMID: 30610025
PMC: PMC6326342
DOI: 10.1136/bmjopen-2018-024446

GACD Hypertension Research Programme , author
Writing Group , author
Peiris D , author
Thompson SR , author
Beratarrechea A , author
Cárdenas MK , author
Diez-Canseco F , author
Goudge J , author
Gyamfi J , author
Hypertension Research Programme members , author

2015-11-01

Implementation science : IS

PMID: 26553092
PMC: PMC4638103
DOI: 10.1186/s13012-015-0331-0

Cindy George , author
Tandi E Matsha , author
Saarah FG Davids , author
Gloudina M Hon , author
U Chikte , author
Rajiv T Erasmus , author
Andre P Kengne , author

2022-03-08

South African Dental Journal

DOI: 10.17159/2519-0105/2022/v77no1a1

Kaze FF , author
Ashuntantang G , author
Kengne AP , author
Hassan A , author
Halle MP , author
Muna W , author

2012-04-01

Hemodialysis international. International Symposium on Home Hemodialysis

PMID: 22541071
DOI: 10.1111/j.1542-4758.2012.00692.x

Nouya AY , author
Nansseu JR , author
Moor VJ , author
Pieme CA , author
Noubiap JJ , author
Tchoula CM , author
Mokette BM , author
Takam RD , author
Tankeu F , author
Ngogang JY , author
Kengne AP , author

2014-10-01

Diabetes research and clinical practice

PMID: 25458342
DOI: 10.1016/j.diabres.2014.09.042

Kengne AP , author
Dzudie A , author
Dongmo L , author

2006-10-01

Neuroepidemiology

PMID: 17068407
DOI: 10.1159/000096609

Mazidi M , author
Heidari-Bakavoli A , author
Khayyatzadeh SS , author
Azarpazhooh MR , author
Nematy M , author
Safarian M , author
Esmaeili H , author
Parizadeh SM , author
Ghayour-Mobarhan M , author
Kengne AP , author
Ferns GA , author

2016-09-01

European journal of clinical nutrition

PMID: 27677365
DOI: 10.1038/ejcn.2016.92

Werfalli M , author
Raubenheimer PJ , author
Engel M , author
Musekiwa A , author
Bobrow K , author
Peer N , author
Hoegfeldt C , author
Kalula S , author
Kengne AP , author
Levitt NS , author

2020-06-01

Systematic reviews

PMID: 32505214
PMC: PMC7275531
DOI: 10.1186/s13643-020-01377-8

Andre Pascal Kengne , author
Eugene Sobngwi , author
Leopold Fezeu , author
Paschal Kum Awah , author
Sylvestre Dongmo , author

Setting-up nurse-led pilot clinics for the management of non-communicable diseases at primary health care level in resource-limited settings of Africa

SOURCE-WORK-ID: BASE:2f524dba93bb9c88e7d0c9c8c6b4ee2362a31d99c2e3d9141c694b747249b13e

Nong-Libend C , author
Menanga AP , author
Kengne AP , author
Dehayem M , author
Sobngwi E , author
Kingue S , author

2012-05-01

Diabetes & metabolism

PMID: 22658546
DOI: 10.1016/j.diabet.2012.02.004

Echouffo-Tcheugui JB , author
Kengne AP , author
Ali MK , author

2018-09-01

Current diabetes reports

PMID: 30229351
DOI: 10.1007/s11892-018-1089-y

Kaze FF , author
Meto DT , author
Halle MP , author
Ngogang J , author
Kengne AP , author

2015-07-01

BMC nephrology

PMID: 26220538
PMC: PMC4518633
DOI: 10.1186/s12882-015-0111-8

Theodosia Adom , author
Anniza De Villiers , author
Thandi Puoane , author
André Pascal Kengne , author

2019-01-01

Abstract Background There is limited data on risk factors associated with childhood overweight and obesity in Ghanaian school children. Therefore, the aim of this study was to assess the prevalence of overweight and obesity and associated risk factors in Ghanaian school children. Methods Data for this study were obtained from a cross-sectional survey of 543 children aged 8 and 11 years, attending private and public primary schools in the Adentan Municipality of Greater Accra Region, Ghana. Anthropometric, dietary, physical activity, sedentary behaviours, sleep duration and socio-demographic data were collected. BMI-for-age Z-scores were used to classify children as overweight/obesity. Multivariable logistic regressions were used to assess the determinants of overweight and obesity. Results The overall prevalence of overweight/obesity was 16.4%. Children living in middle (OR = 1.88; 95% CI = 1.01–3.50) and high socioeconomic status (SES) households (2.58; 1.41–4.70) had increased odds of being overweight or obese compared to those living in low SES household. Attending private school (2.44; 1.39–4.29) and watching television for more than 2 h each day (1.72; 1.05–2.82) were significantly associated with increased likelihood of overweight and obesity. Children who slept for more than 9 h a night (0.53; 0.31–0.88) and walked or cycled to school (0.51; 0.31–0.82) had lower odds of being overweight or obese. Conclusions A number of modifiable risk factors were associated with overweight and obesity in this study. Public health strategies to prevent childhood obesity should target reduction in television watching time, promoting active transport to and from school, and increasing sleep duration.

SOURCE-WORK-ID: BASE:e0592082cf0828d85f2a131c440a75826592abdeed7c417af62cb6bd4d190897
DOI: 10.1186/s40608-019-0234-8

Mbanya V , author
Hussain A , author
Kengne AP , author

2015-05-01

Primary care diabetes

PMID: 25975760
DOI: 10.1016/j.pcd.2015.04.004

Pule GD , author
Ngo Bitoungui VJ , author
Chetcha Chemegni B , author
Kengne AP , author
Wonkam A , author

2016-11-01

Hemoglobin

PMID: 27829299
DOI: 10.1080/03630269.2016.1251453

Feigin VL , author
Krishnamurthi RV , author
Parmar P , author
Norrving B , author
Mensah GA , author
Bennett DA , author
Barker-Collo S , author
Moran AE , author
Sacco RL , author
Truelsen T , author
Davis S , author
Pandian JD , author
GBD 2013 Stroke Panel Experts Group , author

2015-10-01

Neuroepidemiology

PMID: 26505981
PMC: PMC4633282
DOI: 10.1159/000441085

Kengne AP , author
Sobngwi E , author
Echouffo-Tcheugui JB , author
Mbanya JC , author

2013-05-01

Heart (British Cardiac Society)

PMID: 23680890
DOI: 10.1136/heartjnl-2013-303773

Mazidi M , author
Kengne AP , author
Sahebkar A , author
Banach M , author

2017-06-01

Angiology

PMID: 28583002
DOI: 10.1177/0003319717712860

2005-10-28

International journal of epidemiology

BACKGROUND: As the relation between socioeconomic status (SES) and obesity may depend on the stage of development of a country, this relation is assessed in adults from urban Cameroon. METHODS: A sample comprising 1530 women and 1301 men aged 25 years and above, from 1897 households in the Biyem-Assi health area in the capital of Cameroon, Yaoundé, were interviewed about their household amenities, occupation, and education. Weight, height, and waist circumference were measured and subjects were classified as obese if their BMI>or=30 kg/m2 or overweight if BMI was between 25.0 and 29.9 kg/m2. Abdominal obesity was defined by a waist circumference>or=80 cm in women and>or=94 cm in men. RESULTS: Of the sample studied 33% of women and 30% of men were overweight (P<0.08), whereas 22% of women and 7% of men were obese (P<0.001). Abdominal obesity was present in 67% of women and 18% of men (P<0.001). After adjusting for age, leisure time physical activity, alcohol consumption, and tobacco smoking, the prevalence of overweight+obesity, obesity, and abdominal obesity increased with quartiles of household amenities in both genders and with occupational level in men. CONCLUSION: SES is positively associated with adiposity in urban Cameroon after adjusting for confounding factors.

PMID: 16258058
DOI: 10.1093/ije/dyi214

Marie Patrice Halle , author
Gloria Ashuntantang , author
Francois Folefack Kaze , author
Christian Takongue , author
Andre-Pascal Kengne , author

2016-12-01

BMC Nephrology

DOI: 10.1186/s12882-016-0377-5

GBD 2017 Oesophageal Cancer Collaborators , author

2020-04-01

The lancet. Gastroenterology & hepatology

PMID: 32246941
PMC: PMC7232026
DOI: 10.1016/s2468-1253(20)30007-8

Boateng D , author
Agyemang C , author
Beune E , author
Meeks K , author
Smeeth L , author
Schulze M , author
Addo J , author
de-Graft Aikins A , author
Galbete C , author
Bahendeka S , author
Danquah I , author
Agyei-Baffour P , author
Klipstein-Grobusch K , author

2017-11-01

Circulation. Cardiovascular quality and outcomes

PMID: 29150534
DOI: 10.1161/circoutcomes.117.004013

Matsha TE , author
Hartnick MD , author
Kisten Y , author
Eramus RT , author
Kengne AP , author

2013-10-01

Journal of diabetes

PMID: 24028321
DOI: 10.1111/1753-0407.12089

Mazidi M , author
Kengne AP , author
George ES , author
Siervo M , author

2019-08-01

The British journal of nutrition

PMID: 31434580
DOI: 10.1017/s0007114519002149

Katte JC , author
Dzudie A , author
Sobngwi E , author
Mbong EN , author
Fetse GT , author
Kouam CK , author
Kengne AP , author

2014-07-01

BMC public health

PMID: 25000848
PMC: PMC4107975
DOI: 10.1186/1471-2458-14-696

Alain Lekoubou , author
Clovis Nkoke , author
Anastase Dudzie , author
Andre Pascal Kengne , author

2016-01-01

Background: Despite the increasing availability of head computerized tomography (CT) in resource-limited settings, it is unclear if brain-imaging-based diagnosis of stroke affects the outcomes in the absence of dedicated structures for acute stroke management. Objectives: In a major referral hospital in the capital city of Cameroon, we compared in-hospital mortality rates in patients with a WHO-based diagnosis of stroke between participants with and without brain imaging on admission. Methods: Stroke patients with and without admission brain imaging were compared for demographic characteristics, risk factors, clinical and laboratory characteristic, and in-hospital mortality. Heterogeneities in mortality rates (CT vs. No CT) across major subgroups were investigated via interaction tests, and logistic regressions used to adjust for extraneous factors such as age, sex, year of study, residency, history of diabetes and hypertension, history of stroke, Glasgow coma scale, and delay between stroke symptoms onset and hospital admission. Results: Of the 1688 participants included in the final analysis, 1048 (62.1%) had brain imaging. The median age of the non-CT vs. CT groups was 65 vs. 62 years (p-value < 0.0001%). The death rate of non-CT vs. CT groups was 27.5% vs. 16.4% (p < 0.0001). This difference was mostly similar across major subgroups, and robust to the adjustments for confounders (in spite of substantial attenuation), with excess deaths in those with CT ranging from 65% to 149%. Conclusion: In this resource-limited environment, the absence of brain imaging on admission was associated with high in-hospital death from stroke, which was only partially explained by delayed hospitalization with severe disease. These results stressed the importance of scaling up acute stroke management in low- and middle-income countries.

SOURCE-WORK-ID: BASE:6fb2f3d14719c0d5562b07e48d9083fd0a2d26554c47ca8e1395babce1f48a39
DOI: 10.1016/j.ensci.2016.01.003

Pefura Yone EW , author
Kuaban C , author
Kengne AP , author

2012-08-01

BMC infectious diseases

PMID: 22894713
PMC: PMC3482584
DOI: 10.1186/1471-2334-12-190

Zemlin AE , author
Matsha TE , author
Kengne AP , author
Hon GM , author
Erasmus RT , author

2016-09-01

Annals of clinical biochemistry

PMID: 27141013
DOI: 10.1177/0004563216640001

Engel ME , author
Cohen K , author
Gounden R , author
Kengne AP , author
Barth DD , author
Whitelaw AC , author
Francis V , author
Badri M , author
Stewart A , author
Dale JB , author
Mayosi BM , author
Maartens G , author

2017-03-01

The Pediatric infectious disease journal

PMID: 27870815
PMC: PMC5303124
DOI: 10.1097/INF.0000000000001413

GBD 2017 Inflammatory Bowel Disease Collaborators , author

2019-10-01

The lancet. Gastroenterology & hepatology

PMID: 31648971
PMC: PMC7026709
DOI: 10.1016/s2468-1253(19)30333-4

Mohsen Mazidi , author
Andre Pascal Kengne , author
Hassan Vatanparast , author

2017-01-01

Oxidative Medicine and Cellular Longevity

DOI: 10.1155/2017/5427657

Uthman OA , author
Nduka C , author
Watson SI , author
Mills EJ , author
Kengne AP , author
Jaffar SS , author
Clarke A , author
Moradi T , author
Ekström AM , author
Lilford R , author

2018-06-01

BMC infectious diseases

PMID: 29866059
PMC: PMC5987595
DOI: 10.1186/s12879-018-3162-1

NCD Risk Factor Collaboration (NCD-RisC) , author

2019-05-01

Nature

PMID: 31068725
DOI: 10.1038/s41586-019-1171-x

Steve Raoul Ngongang Noumegni , author
Jobert Richie Nansseu , author
Vicky Jocelyne Moor Ama , author
Jean Joel Bigna , author
Felix Kembe Assah , author
Magellan Guewo-Fokeng , author
Steve Leumi , author
Jean-Claude Katte , author
Mesmin Dehayem , author
Andre Pascal Kengne , author
Eugene Sobngwi , author

2017-01-01

Abstract Background Little is known on the magnitude and correlates of insulin resistance in HIV-infected people in Africa. We determined the prevalence of insulin resistance and investigated associated factors in HIV-infected adult Cameroonians. Methods We conducted a cross-sectional study at the Yaoundé Central Hospital, Cameroon; during which we enrolled HIV-infected people aged 30 to 74 years with no previous history of cardiovascular disease. An homeostatic model assessment of insulin resistance (HOMA-IR) like index served to assess insulin sensitivity with insulin resistance defined by values of 2.1 or higher. Results We included 452 patients (20% men). Their mean age was 44.4 ± 9.8 years and 88.5% of them were on antiretroviral therapy (93.3% on first line regimen including Zidovudine, lamivudine and Efavirenz/Nevirapine). Of all participants, 28.5% were overweight, 19.5% had obesity and 2.0% had diabetes. The prevalence of insulin resistance was 47.3% without any difference between patients on ART and those ART-naïve (48.5% vs. 38.5%; p = 0.480). Obesity was the only factor independently associated with insulin resistance (adjusted odds ratio: 2.28; 95% confidence interval: 1.10–4.72). Conclusion Insulin resistance is present in nearly half of HIV-infected patients in Cameroon despite a low prevalence rate of diabetes, and is associated with obesity.

SOURCE-WORK-ID: BASE:ad6d48c1249e06576f3cfbdcf68dc2b94c140b434f43b96c5ac97bb56025d528
DOI: 10.1186/s12944-017-0543-1

Andre Pascal Kengne , author
Anushka Patel , author

2006-01-01

SOURCE-WORK-ID: BASE:fe1f1886f1e53c99667323d494e7b3d9e9943cfe6c877cd18d26047f002dcf8d
DOI: 10.1371/journal.pmed.0030424

Kuguyo O , author
Kengne AP , author
Dandara C , author

2020-06-01

Omics : a journal of integrative biology

PMID: 32552397
DOI: 10.1089/omi.2020.0077

Mohsen Mazidi , author
Andre Pascal Kengne , author
Dimitri P. Mikhailidis , author
Arrigo F. Cicero , author
Maciej Banach , author

2017-01-01

Abstract ; Background and aim: Growing evidence suggests that some of the effects of diet on cardiovascular disease (CVD) occur through mechanisms involving subclinical inflammation. We assessed the relationship between selected dietary constituents and serum high-sensitivity C-reactive protein (hsCRP) concentration in a population-based sample of United States adults. Methods: In this cross-sectional analysis, participants were selected from the US National Health and Nutrition Examination Survey (NHANES) and restricted to those with available data on dietary intake, biochemical and anthropometric measurements from 2001 to 2010. All statistical analyses accounted for the survey design and sample weights by using SPSS Complex Samples v22.0 (IBM Corp, Armonk, NY). Results: Of the 17,689 participants analysed, 8607 (48.3%) were men. The mean age was 45.8 years in the overall sample, 44.9 in men and 46.5 in women ( p = .047). The age-, race-, sex-, energy intake- and body mass index-adjusted mean dietary intakes of total dietary fibre, polyunsaturated fatty-acids, vitamin E, vitamin A, vitamin B6, total folate, vitamin B family, vitamin C, vitamin K, magnesium, iron, copper and potassium monotonically decreased across increasing hsCRP quarters ( p < .001 for all), whereas sugar intake increased ( p < .001). In analysis of covariance adjusted for potential confounders (age-, race-, sex-, energy intake- and body weight-) hsCRP levels increased across increasing quarters of sugar intake ( p < .001). Conclusions: This study provides further evidence of an association between dietary sugar, polyunsaturated fatty-acids, fibre and antioxidant intake and hsCRP levels, a subclinical inflammation marker. hsCRP concentrations are likely modulated by dietary intake.KEY MESSAGES Serum high-sensitivity C-reactive protein (hsCRP) concentration is positively associated with sugar intake, and negatively with the consumption of minerals, vitamins and polyunsaturated fatty-acids (fruit and vegetables). hsCRP concentrations, and accordingly subclinical inflammation, are likely influenced by dietary intake. Serum high-sensitivity C-reactive protein (hsCRP) concentration is positively associated with sugar intake, and negatively with the consumption of minerals, vitamins and polyunsaturated fatty-acids (fruit and vegetables). hsCRP concentrations, and accordingly subclinical inflammation, are likely influenced by dietary intake.

SOURCE-WORK-ID: BASE:0182fa240ccc41ce1277f19a753fd1ad8590de256168dd523d507245f14102a5
DOI: 10.6084/m9.figshare.5032259.v1

Dzudie A , author
Rayner B , author
Ojji D , author
Schutte AE , author
Twagirumukiza M , author
Damasceno A , author
Ba SA , author
Kane A , author
Kramoh E , author
Anzouan Kacou JB , author
Onwubere B , author
Cornick R , author
Sliwa K , author
PASCAR Task Force on Hypertension , author

2017-10-01

Global heart

PMID: 29042191
DOI: 10.1016/j.gheart.2017.06.001

Balti EV , author
Kengne AP , author
Fokouo JVF , author
Nouthé BE , author
Sobngwi E , author

2013-12-01

PloS one

PMC: PMC3866322
DOI: 10.1371/annotation/8410c942-8d5a-44c7-83e0-dc6ffe6b7c85

Chalmers J , author
Kengne AP , author
Joshi R , author
Perkovic V , author
Patel A , author

2007-06-01

Journal of hypertension. Supplement : official journal of the International Society of Hypertension

PMID: 17579315
DOI: 10.1097/01.hjh.0000271506.69949.46

Kim Anh Nguyen , author
Naeemah Abrahams , author
Rachel Jewkes , author
Shibe Mhlongo , author
Soraya Seedat , author
Bronwyn Myers , author
Carl Lombard , author
Claudia Garcia-Moreno , author
Esnat Chirwa , author
Andre Pascal Kengne , author
Nasheeta Peer , author

2022-03-29

International Journal of Environmental Research and Public Health

DOI: 10.3390/ijerph19074026

Moloi MW , author
Kajawo S , author
Noubiap JJ , author
Mbah IO , author
Ekrikpo U , author
Kengne AP , author
Bello AK , author
Okpechi IG , author

2018-05-01

BMJ open

PMID: 29794094
PMC: PMC5988068
DOI: 10.1136/bmjopen-2017-020464

Lekoubou A , author
Philippeau F , author
Derex L , author
Olaru A , author
Gouttard M , author
Vieillart A , author
Kengne AP , author

2013-12-01

Neurological research

PMID: 24620962
DOI: 10.1179/1743132813y.0000000302

Matsha TE , author
Hassan MS , author
Hon GM , author
Soita DJ , author
Kengne AP , author
Erasmus RT , author

2013-05-01

International journal of cardiology

PMID: 23669104
DOI: 10.1016/j.ijcard.2013.03.150

Matsha TE , author
Kengne AP , author
Masconi KL , author
Yako YY , author
Erasmus RT , author

2015-06-01

BMC genetics

PMID: 26112018
PMC: PMC4482162
DOI: 10.1186/s12863-015-0228-6

Matsha TE , author
Yako YY , author
Rensburg MA , author
Hassan MS , author
Kengne AP , author
Erasmus RT , author

2013-04-01

BMC nephrology

PMID: 23547953
PMC: PMC3637389
DOI: 10.1186/1471-2369-14-75

Mazidi M , author
Shivappa N , author
Wirth MD , author
Hebert JR , author
Kengne AP , author

2018-11-01

European journal of clinical nutrition

PMID: 30451987
DOI: 10.1038/s41430-018-0364-y

Eric Walter Pefura-Yone , author
André Pascal Kengne , author
Emmanuel Afane-Ze , author
Christopher Kuaban , author

Background German cockroach or Blattella germanica is commonly found in homes across the inter-tropical region. The contribution of sensitisation to Blattella germanica in people with asthma in sub-Saharan Africa has not received attention. The aim of this study was to assess the prevalence and investigate the predicting factors of sensitisation to Blattella germanica in patients with asthma in Yaounde, Cameroon.Methods This was a cross-sectional study conducted between January 2012 and June 2013. All patients (aged 15 years and above) with asthma, receiving care at the Yaounde Jamot Hospital and the CEDIMER medical practice during the study period and who had received a prick skin testing for perennial aeroallergens were included in the study.Results The final sample comprised 184 patients including 123 (66.8%) women. The median age (25th-75th percentiles) was 38 (24–54) years. Prick skin test for Blattella germanica was positive in 47 (25.5%) patients. Sensitisation to Blattella germanica was associated with a sensitisation to mite in 41 (87.2%) patients, a sensitisation to Alternaria in 18 (38.3%) patients, and a sensitisation to cat or dog dander in 7 (14.9%) patients. Independent predicting factors of a sensitisation to Blattella germanica were the sensitisation to Blomia tropicalis [adjusted odd ratio (95% confidence interval) 4.10 (1.67-10.04), p = 0.002] and sensitisation to Alternaria [3.67 (1.53-7.46), p = 0.003].Conclusions Sensitisation to Blattella germanica is present in about a quarter of adult patients with asthma in Yaounde. Sensitisation to Alternaria and Blomia tropicalis appears to be a powerful predicting factor of sensitisation to Blattella germanica in this setting. Keywords: Asthma, Blattella, Allergy, Aeroallergens, Africa

SOURCE-WORK-ID: BASE:64e856f6649feb79b5ad627dac6e134e8740db146c8052206f8be9ee84c4c87b
DOI: 10.1186/1939-4551-7-22

Eric Walter Pefura-Yone , author
Emmanuel Soh , author
André Pascal Kengne , author
Adamou Dodo Balkissou , author
Christopher Kuaban , author

2013-01-01

Summary: Purpose: To assess the prevalence and determinants of non-adherence to antiretroviral therapy (ART) as well as the concordance of two screening criteria in a major center for human immunodeficiency virus (HIV) treatment in Yaounde, Cameroon. Methods: In 2011, we conducted a cross-sectional study involving a random sample of 889 adults (age > 18 years, 67.9% women) infected with HIV who were receiving chronic care at the Yaounde Jamot Hospital. Adherence was assessed via self-administered questionnaires using the Community Programs for Clinical Research on AIDS (CPCRA) index and the Center for Adherence Support Evaluation (CASE) index. Results: The prevalence of non-adherence to ART was 22.5% based on the CPCRA index and 34.9% based on the CASE index, with a low agreement between the two indexes [kappa = 0.37 (95% confidence interval 0.31–0.44)]. Independent determinants of CPCRA-diagnosed non-adherence were as follows: being a remunerated employee [odds ratio (95% confidence interval): 1.61 (1.14–2.28)], Pentecostal Christianity [2.18 (1.25–3.80)], alcohol consumption [1.65 (1.16–2.34)] and non-adherence to cotrimoxazole prophylaxis [5.73 (3.92–8.38)]. The equivalents for CASE-diagnosed non-adherence were [1.59 (1.19–2.12)], [1.83 (1.36–2.47)], [1.70 (1.27–2.28)], respectively, in addition to association with changes to the ART regimen [1.61 (1.17–2.20)]. Conclusions: Non-adherence to ART remains high in this population. The careful evaluation of patients for the presence of determinants of non-adherence identified in this study may aid ART optimization. Keywords: Antiretroviral therapy, Adherence, HIV infection, Cameroon

SOURCE-WORK-ID: BASE:126fd8a5878afa63d57c9cfc8df3df5b3d8c2d5d13f496a9058c8b072edcce1b
DOI: 10.1016/j.jiph.2013.02.003

Riddell MA , author
Edwards N , author
Thompson SR , author
Bernabe-Ortiz A , author
Praveen D , author
Johnson C , author
Kengne AP , author
Liu P , author
McCready T , author
Ng E , author
Nieuwlaat R , author
Ovbiagele B , author
Owolabi M , author
GACD Hypertension Research Programme , author

2017-03-01

Globalization and health

PMID: 28298233
PMC: PMC5353794
DOI: 10.1186/s12992-017-0242-8

GBD 2017 Gastro-oesophageal Reflux Disease Collaborators , author

2020-03-01

The lancet. Gastroenterology & hepatology

PMID: 32178772
PMC: PMC7232025
DOI: 10.1016/s2468-1253(19)30408-x

Igwesi-Chidobe CN , author
Godfrey EL , author
Kengne AP , author

2015-08-01

BMJ open

PMID: 26270945
PMC: PMC4538245
DOI: 10.1136/bmjopen-2015-008036

Ataklte F , author
Erqou S , author
Kaptoge S , author
Taye B , author
Echouffo-Tcheugui JB , author
Kengne AP , author

2014-11-01

Hypertension (Dallas, Tex. : 1979)

PMID: 25385758
DOI: 10.1161/hypertensionaha.114.04394

Wang H , author
Liddell CA , author
Coates MM , author
Mooney MD , author
Levitz CE , author
Schumacher AE , author
Apfel H , author
Iannarone M , author
Phillips B , author
Lofgren KT , author
Sandar L , author
Dorrington RE , author
Rakovac I , author
Murray CJ , author

2014-05-01

Lancet (London, England)

PMID: 24797572
PMC: PMC4165626
DOI: 10.1016/S0140-6736(14)60497-9

Odukoya OO , author
Ohazurike C , author
Akanbi M , author
O'Dwyer LC , author
Isikekpei B , author
Kuteyi E , author
Ameh IO , author
Osadiaye O , author
Adebayo K , author
Usinoma A , author
Adewole A , author
Odunukwe N , author
Okuyemi K , author
Kengne AP , author

2021-06-01

JMIR mHealth and uHealth

PMID: 34106075
DOI: 10.2196/20330

Kaze FF , author
Kengne AP , author
Atanga LC , author
Monny Lobe M , author
Menanga AP , author
Halle MP , author
Chetcha Chemegni B , author
Ngo Sack F , author
Kingue S , author
Ashuntantang G , author

2012-10-01

Clinical kidney journal

PMID: 27818746
PMC: PMC5094388
DOI: 10.1093/ckj/sfs100

GBD 2020 , author
Release 1 , author
Vaccine Coverage Collaborators , author

2021-07-01

Lancet (London, England)

PMID: 34273291
PMC: PMC8358924
DOI: 10.1016/s0140-6736(21)00984-3

Fezeu LK , author
Assah FK , author
Balkau B , author
Mbanya DS , author
Kengne AP , author
Awah PK , author
Mbanya JC , author

2008-03-01

Obesity (Silver Spring, Md.)

PMID: 18356839
DOI: 10.1038/oby.2008.44

Kengne AP , author
Dzudie AI , author
Fezeu LL , author
Mbanya JC , author

2006-03-01

The international journal of lower extremity wounds

PMID: 16543215
DOI: 10.1177/1534734606286455

Kengne AP , author
Awah PK , author
Fezeu L , author
Mbanya JC , author

2007-03-01

African health sciences

PMID: 17604525
PMC: PMC2366125
DOI: 10.5555/afhs.2007.7.1.38

Vergotine Z , author
Kengne AP , author
Erasmus RT , author
Yako YY , author
Matsha TE , author

2014-08-01

International journal of endocrinology

PMID: 25197274
PMC: PMC4150434
DOI: 10.1155/2014/187985

Aminde LN , author
Takah NF , author
Noubiap JJ , author
Tindong M , author
Ngwasiri C , author
Jingi AM , author
Kengne AP , author
Dzudie A , author

2015-11-01

BMC public health

PMID: 26545721
PMC: PMC4636782
DOI: 10.1186/s12889-015-2468-9

Moons KG , author
Kengne AP , author
Woodward M , author
Royston P , author
Vergouwe Y , author
Altman DG , author
Grobbee DE , author

2012-03-01

Heart (British Cardiac Society)

PMID: 22397945
DOI: 10.1136/heartjnl-2011-301246

van Dieren S , author
Kengne AP , author
Chalmers J , author
Beulens JW , author
Cooper ME , author
Grobbee DE , author
Harrap S , author
Mancia G , author
Neal B , author
Patel A , author
Poulter N , author
van der Schouw YT , author
Woodward M , author
Zoungas S , author

2012-06-01

Diabetes research and clinical practice

PMID: 22677192
DOI: 10.1016/j.diabres.2012.05.002

GBD 2016 Traumatic Brain Injury and Spinal Cord Injury Collaborators , author

2018-11-01

The Lancet. Neurology

PMID: 30497965
PMC: PMC6291456
DOI: 10.1016/S1474-4422(18)30415-0

Eric Vounsia Balti , author
André Pascal Kengne , author
Jean Valentin Fogha Fokouo , author
Brice Enid Nouthé , author
Eugene Sobngwi , author

BACKGROUND AND PURPOSE: Determinants of post-acute stroke outcomes in Africa have been less investigated. We assessed the association of metabolic syndrome (MetS) and insulin resistance with post-stroke mortality in patients with first-ever-in-lifetime stroke in the capital city of Cameroon (sub-Saharan Africa). METHODS: Patients with an acute first-stroke event (n = 57) were recruited between May and October 2006, and followed for 5 years for mortality outcome. MetS definition was based on the Joint Interim Statement 2009, insulin sensitivity/resistance assessed via glucose-to-insulin ratio, quantitative insulin sensitivity check index and homeostatic model assessment. RESULTS: Overall, 24 (42%) patients deceased during follow-up. The prevalence of MetS was higher in patients who died after 28 days, 1 year and 5 years from any cause or cardiovascular-related causes (all p≤0.040). MetS was associated with an increased overall mortality both after 1 year (39% vs. 9%) and 5 years of follow-up (55% vs. 26%, p = 0.022). Similarly, fatal events due to cardiovascular-related conditions were more frequent in the presence of MetS both 1 year (37% vs. 9%) and 5 years after the first-ever-in-lifetime stroke (43% vs. 13%, p = 0.017). Unlike biochemical measures of insulin sensitivity and resistance (non-significant), in age- and sex-adjusted Cox models, MetS was associated with hazard ratio (95% CI) of 2.63 (1.03-6.73) and 3.54 (1.00-12.56) respectively for all-cause and cardiovascular mortality 5 years after stroke onset. CONCLUSION: The Joint Interim Statement 2009 definition of MetS may aid the identification of a subgroup of black African stroke patients who may benefit from intensification of risk factor management.

SOURCE-WORK-ID: BASE:94441a9b51a390343ad9391097e09e8e7108f9227ccf158cbd2c198e3540f2f6
DOI: 10.1371/journal.pone.0060117

Carmen Pheiffer , author
Victoria Pillay-van Wyk , author
Eunice Turawa , author
Naomi Levitt , author
Andre P. Kengne , author
Debbie Bradshaw , author

2021-05-30

International Journal of Environmental Research and Public Health

DOI: 10.3390/ijerph18115868

Di Cesare M , author
Sorić M , author
Bovet P , author
Miranda JJ , author
Bhutta Z , author
Stevens GA , author
Laxmaiah A , author
Kengne AP , author
Bentham J , author

2019-11-01

BMC medicine

PMID: 31760948
PMC: PMC6876113
DOI: 10.1186/s12916-019-1449-8

Muyunda Mutemwa , author
Nasheeta Peer , author
Anniza De Villiers , author
Mieke Faber , author
Andre-Pascal Kengne , author

2020-04-21

Southern African Journal of HIV Medicine

DOI: 10.4102/sajhivmed.v21i1.1072

Peer N , author
Naicker A , author
Khan M , author
Kengne AP , author

2020-07-01

SAGE open medicine

PMID: 32676190
PMC: PMC7340350
DOI: 10.1177/2050312120936907

Anastase, Dzudie , author
Suiru, Dzekem , author
Andre, Pascal Kengne , author

2017-01-01

SOURCE-WORK-ID: BASE:3c7f00a153fef5af39876c7c50f1d068308a4d5219e6cd47dd495e6527440071

Macharia M , author
Kengne AP , author
Blackhurst DM , author
Erasmus RT , author
Matsha TE , author

2013-07-01

Journal of clinical pathology

PMID: 23903005
DOI: 10.1136/jclinpath-2013-201646

NCD Risk Factor Collaboration (NCD-RisC) , author

2020-06-01

Nature

PMID: 32494083
PMC: PMC7332422
DOI: 10.1038/s41586-020-2338-1

Kuate-Tegueu C , author
Temfack E , author
Ngankou S , author
Doumbe J , author
Djientcheu VP , author
Kengne AP , author

2015-05-01

Journal of the neurological sciences

PMID: 26048049
DOI: 10.1016/j.jns.2015.05.035

Davidson FE , author
Matsha TE , author
Erasmus RT , author
Ismail S , author
Kengne AP , author
Goedecke JH , author

2020-04-01

European journal of clinical nutrition

PMID: 32322047
DOI: 10.1038/s41430-020-0631-6

NCD Risk Factor Collaboration (NCD-RisC) , author

2021-08-01

Lancet (London, England)

PMID: 34450083
DOI: 10.1016/s0140-6736(21)01330-1

Davids SF , author
Matsha TE , author
Peer N , author
Erasmus RT , author
Kengne AP , author

2019-11-01

Frontiers in endocrinology

PMID: 31781031
PMC: PMC6851026
DOI: 10.3389/fendo.2019.00753

Aminde LN , author
Dzudie A , author
Kengne AP , author

2016-02-01

BMJ open

PMID: 26911585
PMC: PMC4769384
DOI: 10.1136/bmjopen-2015-010097

Kuate D , author
Kengne AP , author
Biapa CP , author
Azantsa BG , author
Abdul Manan Bin Wan Muda W , author

2015-05-01

Lipids in health and disease

PMID: 26003803
PMC: PMC4448292
DOI: 10.1186/s12944-015-0051-0

Kengne AP , author
Czernichow S , author
Huxley R , author
Grobbee D , author
Woodward M , author
Neal B , author
Zoungas S , author
Cooper M , author
Glasziou P , author
Hamet P , author
Harrap SB , author
Mancia G , author
Poulter N , author
ADVANCE Collaborative Group , author

2009-05-01

Hypertension (Dallas, Tex. : 1979)

PMID: 19470869
DOI: 10.1161/hypertensionaha.109.133041

Davidson FE , author
Matsha TE , author
Erasmus RT , author
Kengne AP , author
Goedecke JH , author

2019-11-01

Diabetology & metabolic syndrome

PMID: 31719847
PMC: PMC6839066
DOI: 10.1186/s13098-019-0483-1

Peprah E , author
Armstrong-Hough M , author
Cook S , author
Mukasa B , author
Taylor J , author
Xu H , author
Chang L , author
Gyamfi J , author
Ryan N , author
Ojo T , author
Snyder A , author
Iwelunmor J , author
Ezechi O , author
Iyegbe C , author
Pascal Kengne A , author

2021-03-01

International journal of environmental research and public health

PMC: PMC8003038

Kengne AP , author
Dzudie A , author
Sobngwi E , author

2008-01-01

Vascular health and risk management

PMID: 18629376
PMC: PMC2464771
DOI: 10.2147/vhrm.2008.04.01.123

Yone EW , author
Balkissou AD , author
Kengne AP , author
Kuaban C , author

2012-08-01

BMC pulmonary medicine

PMID: 22935579
PMC: PMC3495717
DOI: 10.1186/1471-2466-12-46

Adom T , author
Puoane T , author
De Villiers A , author
Kengne AP , author

2017-02-01

BMJ open

PMID: 28399512
PMC: PMC5337729
DOI: 10.1136/bmjopen-2016-013541

Gary Maartens , author
Annemie Stewart , author
Rulan Griesel , author
Andre P. Kengne , author
Felix Dube , author
Mark Nicol , author
Molebogeng X. Rangaka , author
Marc Mendelson , author

2018-07-23

Southern African Journal of HIV Medicine

DOI: 10.4102/sajhivmed.v19i1.851

Masoud M , author
Kengne AP , author
Erasmus RT , author
Hon GM , author
Macharia M , author
Matsha TE , author

2018-03-01

Indian journal of clinical biochemistry : IJCB

PMID: 31391720
DOI: 10.1007/s12291-018-0748-8