|Call||Senior Fellowship (SF)|
Immune reconstitution inflammatory syndrome (IRIS) in schistosomiasis patients undergoing HAART
To study the Immunopathogenesls, clinical aspects and management of manifestation of IRIS in HIV-schistosome co-infection patients undergoing HAART In western Kenya. Schistosome infections are common in the same areas where HIV prevalence is also high.
|Kenya Medical Research Institute (KEMRI)||Kenya|
|Robert Colebunders||Prince Leopold Institute of Tropical Medicine (ITM)||Belgium|
|Diana Karanja||Kenya Medical Research Institute (KEMRI)||Kenya|
|Luc Kestens||Prince Leopold Institute of Tropical Medicine (ITM)||Belgium|
|Erick Muok||Kenya Medical Research Institute (KEMRI)||Kenya|
|Katja Polman||Prince Leopold Institute of Tropical Medicine (ITM)||Kenya|
Prevalence study on IRIS in schistomiasis on HAART
622 HIV-positive patients were followed. In the first year of follow up 12 patients expressed signs and symptoms of IRIS of whom two met the case definition of IRIS. As a requirement for all staff participants on this project, GCP/GCLP training was provided online from the EDCTPsponsored AMANET online courses.
|Ogola GO, Ouma C, Jura WG, Muok EO, Colebunders R, Mwinzi PN. A non-synonymous polymorphism in IL-23R Gene (rs1884444) is associated with reduced risk to schistosomiasis-associated Immune Reconstitution Inflammatory Syndrome in a Kenyan population. BMC Infect Dis. 2014 Jun 10;14(1):316. doi:10.1186/1471-2334-14-316.|